Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce is an irresistible dish that brings a burst of flavor to your table. Perfect for weeknight dinners or special occasions, this creamy pasta combines the richness of garlic butter with zesty Cajun spices and a delightful cheese blend. You’ll love how easy it is to whip up this satisfying meal that will leave everyone asking for seconds.
Why You’ll Love This Recipe
- Quick Preparation: This dish can be made in just 30 minutes, making it ideal for busy evenings.
- Flavor Explosion: The combination of garlic, Cajun seasoning, and creamy cheese creates a rich and bold flavor profile.
- Family-Friendly: With its comforting ingredients, this recipe is sure to please both kids and adults alike.
- Versatile Ingredients: Feel free to customize by adding vegetables or swapping meats based on your preferences.
- One-Pot Wonder: Most of the cooking happens in one skillet, meaning less cleanup for you!
Tools and Preparation
Before diving into cooking, gather your tools and ensure you have everything you need to make Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce.
Essential Tools and Equipment
- Large pot
- Skillet
- Spatula
- Measuring cups and spoons
- Colander
Importance of Each Tool
- Large pot: Essential for boiling pasta efficiently while allowing space for stirring.
- Skillet: Perfect for sautéing ingredients and creating the luscious cheese sauce.
- Spatula: Helps break up the meat while cooking and ensures even mixing of flavors.
Ingredients
For the Pasta
- 1 lb ground beef
- 12 oz penne pasta
For the Sauce
- 2 tablespoons butter
- 4 cloves garlic, minced
- 1 tablespoon Cajun seasoning
- 1 teaspoon Italian seasoning (optional but recommended)
- 1 cup heavy cream
- 1 cup Velveeta cheese, cubed
- 1 cup shredded mozzarella cheese
- ½ cup grated Parmesan cheese
- Salt and black pepper to taste
For Garnish
- 2 tablespoons fresh parsley, finely chopped
How to Make Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce
Step 1: Boil the Pasta
Bring a large pot of salted water to a boil. Cook the penne pasta according to package directions until al dente. Drain and set aside.
Step 2: Sauté Garlic
In a large skillet over medium heat, melt the butter. Add the minced garlic and sauté for 1 minute until fragrant.
Step 3: Cook the Beef
Add the ground beef to the skillet. Cook until browned and fully cooked, breaking it up with a spatula. Drain any excess fat.
Step 4: Season the Meat
Sprinkle the Cajun seasoning and Italian seasoning over the beef. Stir well to coat the meat with the seasonings.
Step 5: Create the Sauce
Pour in the heavy cream and reduce heat to medium-low. Add the Velveeta cubes and stir until melted into a smooth sauce.
Step 6: Add Cheeses
Stir in the mozzarella and Parmesan cheeses, mixing until everything is melted and thickened into a creamy sauce.
Step 7: Combine Pasta and Sauce
Add the cooked penne pasta to the skillet. Toss thoroughly to coat all pasta in the cheesy sauce.
Step 8: Season to Taste
Taste your dish! Adjust with salt and pepper as needed. Let it simmer for a couple more minutes if you’d like it thicker.
Step 9: Serve Hot
Serve hot, garnished with chopped parsley if desired. Enjoy your flavorful Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce!
How to Serve Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce
Serving Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce is as important as making it. The right presentation and accompaniments can elevate this delicious dish. Here are some creative ways to serve it.
Plating Suggestions
- Garnish with Fresh Herbs: Sprinkle chopped parsley on top for a burst of color and freshness.
- Add a Dash of Hot Sauce: For those who enjoy a kick, serve with a side of hot sauce to drizzle over the dish.
Accompaniments
- Garlic Bread: Serve warm garlic bread on the side for a perfect pairing that complements the flavors.
- Green Salad: A light, crisp salad balances the richness of the pasta and adds a refreshing crunch.
- Grilled Vegetables: Add grilled zucchini or bell peppers for a smoky flavor that pairs well with the creamy sauce.
How to Perfect Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce
To make your Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce even better, consider these helpful tips.
- Bold Seasoning: Adjust the amount of Cajun seasoning based on your spice preference. Don’t hesitate to experiment!
- Quality Cheeses: Use fresh mozzarella and real Parmesan cheese for the best flavor and creaminess.
- Pasta Cooking Time: Cook the penne just until al dente to ensure it holds its shape when mixed with the sauce.
- Cream Consistency: If you prefer a thicker sauce, let it simmer longer after adding the cheeses to achieve your desired texture.
- Leftover Storage: Store leftovers in an airtight container for up to three days. Reheat gently on low heat.
- Extra Creamy Sauce: For an ultra-creamy sauce, add a bit more heavy cream or cheese as needed while stirring.

Best Side Dishes for Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce
Pairing sides with Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce can enhance your meal experience. Here are some great suggestions.
- Caesar Salad: A classic Caesar salad adds crisp romaine and tangy dressing that cuts through the richness.
- Roasted Asparagus: Lightly seasoned roasted asparagus provides a healthy contrast to the creamy pasta.
- Coleslaw: A crunchy coleslaw brings a refreshing crunch that complements the dish beautifully.
- Corn on the Cob: Grilled or boiled corn pairs well, offering sweetness alongside the savory flavors.
- Baked Potatoes: Fluffy baked potatoes can be topped with sour cream and chives for an added treat.
- Stuffed Mushrooms: These bite-sized delights filled with cheese and herbs make for excellent finger food beside the pasta.
Common Mistakes to Avoid
Cooking can be tricky, especially when making Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce. Here are some common mistakes to watch out for.
- Not cooking the pasta al dente: Overcooking the penne can lead to mushiness. Always follow package instructions and taste test for that perfect texture.
- Skipping the seasoning: Cajun seasoning is essential for flavor. Don’t skip it, and feel free to adjust based on your spice preference for a more personalized taste.
- Using low-quality cheese: Cheap cheeses may not melt well, affecting the sauce’s creaminess. Opt for quality Velveeta and mozzarella to achieve that velvety texture.
- Rushing the simmer time: Allowing the sauce to simmer enhances flavors and thickens it properly. Take your time; this step is crucial for a rich dish.
- Overlooking garnishes: Fresh parsley adds a beautiful touch and fresh flavor. Don’t forget to sprinkle some on top before serving for added color and taste.
Refrigerator Storage
- Store leftovers in an airtight container.
- Garlic Butter Cajun Beef Penne can be refrigerated for up to 3-4 days.
Freezing Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce
- Use freezer-safe containers or heavy-duty freezer bags.
- This dish can be frozen for up to 2-3 months.
Reheating Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce
- Oven: Preheat oven to 350°F (175°C). Place in an oven-safe dish, cover with foil, and heat until warmed through, about 15-20 minutes.
- Microwave: Place portions in a microwave-safe bowl, cover loosely, and heat on high for 1-2 minutes, stirring halfway through.
- Stovetop: In a skillet over medium heat, add a splash of cream or milk if needed. Stir until heated through.

Frequently Asked Questions
What makes Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce unique?
This dish combines robust Cajun spices with creamy cheeses, creating a comforting yet exciting meal that stands out from traditional pasta recipes.
Can I customize the spices in Garlic Butter Cajun Beef Penne?
Absolutely! Feel free to add more heat with cayenne pepper or even substitute the Cajun seasoning with your favorite blend.
What can I serve with Garlic Butter Cajun Beef Penne?
This dish pairs wonderfully with a simple green salad or garlic bread for a complete meal experience.
How do I ensure the cheese sauce is smooth?
Make sure to melt the Velveeta cheese on low heat and stir continuously until fully incorporated into the sauce.
Final Thoughts
Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce is not only delicious but also versatile. You can easily customize it by adding vegetables or swapping proteins. Give this recipe a try; it’s sure to become a favorite in your household!

Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce
- Total Time: 30 minutes
- Yield: Serves 4
Description
Garlic Butter Cajun Beef Penne in Velvety Cheese Sauce is a flavorful pasta dish that blends the richness of garlic butter with zesty Cajun spices and a creamy cheese sauce. Ready in just 30 minutes, this recipe is perfect for busy weeknight dinners or special occasions. The combination of tender penne pasta, savory ground beef, and a delightful mix of cheeses creates a satisfying meal that will have everyone asking for more. Customize it easily by adding your favorite vegetables or adjusting the spice level to suit your taste. This one-pot wonder not only simplifies cooking but also minimizes cleanup, making it an ideal choice for any home chef.
Ingredients
- 1 lb ground beef
- 12 oz penne pasta
- 2 tablespoons butter
- 4 cloves garlic, minced
- 1 tablespoon Cajun seasoning
- 1 cup heavy cream
- 1 cup Velveeta cheese, cubed
- 1 cup shredded mozzarella cheese
- Fresh parsley for garnish
Instructions
- Boil the penne pasta in salted water until al dente, then drain.
- In a skillet, melt butter and sauté minced garlic until fragrant.
- Add ground beef; cook until browned and drain excess fat.
- Stir in Cajun seasoning and Italian seasoning.
- Pour in heavy cream; add Velveeta cheese and stir until melted.
- Mix in mozzarella and Parmesan cheeses until smooth.
- Combine cooked penne with the sauce; toss to coat evenly.
- Adjust seasoning with salt and pepper before serving hot, garnished with parsley.
- Prep Time: 10 minutes
- Cook Time: 20 minutes
- Category: Main
- Method: Skillet
- Cuisine: Cajun
Nutrition
- Serving Size: 1 cup (240g)
- Calories: 600
- Sugar: 3g
- Sodium: 800mg
- Fat: 36g
- Saturated Fat: 20g
- Unsaturated Fat: 14g
- Trans Fat: 0g
- Carbohydrates: 44g
- Fiber: 2g
- Protein: 28g
- Cholesterol: 90mg
Keywords: Adjust Cajun seasoning based on your spice preference. For extra creaminess, add more heavy cream or cheese while stirring. Store leftovers in an airtight container for up to three days or freeze for later enjoyment.